Cancer is not one disease, but rather many related diseases. Cancer is typed according to the part of the body where it is located and the kind of cells that comprise it. The most common types of cancer cells and their locations are:

>>Carcinomas originate in skin tissue or tissues that line the body cavities and such internal organs as the lungs, breast, colon, and intestines.
>>Sarcomas grow in bones and connective tissues between organs and skin, and sometimes spread into the blood or lymphatic system.
>>Lymphomas are cancers of the lymphatic system, usually occurring in the lymph nodes.
>>Leukemias form in the blood or circulatory system, particularly in the bone marrow, which is the site of blood cell production.
>>Myelomas are tumors of bone marrow cells and frequently form simultaneously in many sites, including the ribs, vertebrae, and pelvic bones.

TYPES OF CANCER:

Bone Cancer

( Ewing’s Sarcoma, Osteosarcoma, Rhabdomysarcoma)
Ewing’s Family of Tumors: The Ewing's family of tumors include: Ewing's tumor of bone; extraosseus Ewing's (tumor growing outside of the bone); primitive neuroectodermal tumor(PNET), also known as peripheral neuroepithelioma; and Askin's tumor (PNET of the chest wall). These tumors are rare diseases in which cancer (malignant)cells are found in the bone and soft tissues. Ewing's family of tumors most frequently occurs in teenagers.

Osteosarcoma: Osteosarcoma is a disease in which cancer (malignant) cells are found in the bone. It is the most common type of bone cancer. In children, it occurs most commonly in the bones around the knee. Osteosarcoma most often occurs in adolescents and young adults.

Brain tumors:
Cancer can occur in any part of the brain or spinal cord. Cancer cells are abnormal cells that divide too often and without any order (Free Radicals). In 1997, about 18,000 new brain tumors were diagnosed, a 50% increase from only ten years ago. They are rare tumors, representing only 1.5% of all cancers reported in the United States. The causes of central nervous system tumors are not known, and scientists cannot explain why brain tumors develop in healthy adults. Certain factors, however, have been identified that may increase a person's chance of developing a brain tumor. For example, workers in the oil refining, rubber manufacturing, and drug manufacturing industries have higher rates of certain types of brain tumors. Researchers are also studying families in whom multiple members have developed the same type of brain tumor to see whether heredity plays a role. They are also looking at the connection between viral infections and exposure to radiation and the development of brain tumors.

There is no research to suggest that head injuries cause or increase a person's risk for developing a brain tumor. Because most patients diagnosed with a brain tumor have no identifiable risk factors, it is believed that brain tumors result from a number of factors acting together. Tumors which start in the brain are called primary brain tumors and are classified according to the kind of cell from which the tumor seems to originate. The most common primary brain tumor in adults comes from cells in the brain called astrocytes that make up the blood-brain barrier and contribute to the nutrition of the central nervous system. These tumors are called gliomas (astrocytoma, anaplastic astrocytoma, or glioblastoma multiforme) and account for 65% of all primary central nervous system tumors.

Breast Cancer:
The breast is a collection of glands and fatty tissue that lies between the skin and the chest wall. The glands inside the breast produce milk after a woman has a baby. Each gland is also called a lobule, and many lobules make up a lobe. There are 15 to 20 lobes in each breast. The milk gets to the nipple from the glands by way of tubes called ducts. The glands and ducts get bigger when a breast is filled with milk, but the tissue that is most responsible for the size and shape the breast is the fatty tissue. There are also blood vessels and lymph vessels in the breast. Lymph is a clear liquid waste product that gets drained out of the breast into lymph nodes. Lymph nodes are small, pea-sized pieces of tissue that filter and clean the lymph. Most lymph nodes that drain the breast are under the arm in what is called the axilla.

Breast Cancer happens when cells in the breast begin to grow ( Free Radicals)out of control and can then invade nearby tissues or spread throughout the body. Large collections of this out of control tissue are called tumors. However, some tumors are not really cancer because they cannot spread or threaten someone's life. These are called benign tumors. The tumors that can spread throughout the body or invade nearby tissues are considered cancer and are called malignant tumors. Theoretically, any of the types of tissue in the breast can form a cancer, but usually it comes from either the ducts or the glands. Because it may take months to years for a tumor to get large enough to feel in the breast, we screen for tumors with mammograms, which can sometimes see disease before we can feel it.

Endocrine Cancers

(Adrenal Cancers, Pancreatic Cancer, Parathyroid Cancer, Pituitary Cancer, Thyroid Cancer)

Adrenal cancers: Pheochromocytoma, a rare cancer, is a disease in which cancer (malignant) cells are found in special cells in the body called chromaffin cells. Most pheochromocytomas start inside the adrenal gland (the adrenal medulla) where most chromaffin cells are located. There are two adrenal glands, one above each kidney in the back of the upper abdomen. Cells in the adrenal glands make important hormones that help the body work properly. Usually pheochromocytoma affects only one adrenal gland. Pheochromocytoma may also start in other parts of the body, such as the area around the heart or bladder. Most tumors that start in the chromaffin cells do not spread to other parts of the body and are not cancer. These are called benign tumors. If a tumor is found, the doctor will need to determine whether it is cancer or benign.

Pheochromocytomas often cause the adrenal glands to make too many hormones called catecholamines. The extra catecholamines cause high blood pressure(hypertension), which can cause headaches, sweating, pounding of the heart, pain in the chest, and a feeling of anxiety. High blood pressure that goes on for a long time without treatment can lead to heart disease, stroke, and other major health problems.

Pancreatic Cancer: Pancreatic cancer happens when cells in the pancreas begin to grow out of control(Free Radicals). These cancer cells then have the ability to spread to nearby lymph nodes and organs (such as the liver and lungs). When cancer spreads, it is called metastatic. About seventy percent of pancreatic cancers occur in the head of the pancreas, and most of these begin in the ducts that carry the enzymes.

Parathyroid cancer: A very rare cancer, is a disease in which cancer(malignant) cells are found in the tissues of the parathyroid gland. The parathyroid gland is at the base of the neck, near the thyroid gland. The parathyroid gland makes a hormone called parathyroid hormone (PTH), orparathormone, which helps the body store and use calcium.

Problems with the parathyroid gland are common and are usually not caused by cancer. If parathyroid cancer is found, the parathyroid gland may be making too much PTH. This causes too much calcium to be found in the blood. The extra PTH also takes calcium from the bones, which causes pain in the bones, kidney problems, and other types of problems. There are other conditions that can cause the parathyroid gland to make too much PTH. It is important for a doctor to determine what is causing the extra PTH. Hyperparathyroidism is a condition which can cause the body to make extra PTH. If hyperparathyroidism runs in the family, there is a greater chance of getting this type of cancer

Pituitary tumors: are tumors found in the pituitary gland, a small organ about the size of a pea in the center of the brain just above the back of the nose. The pituitary gland makes hormones that affect the growth and the functions of other glands in the body.

Most pituitary tumors are benign. This means that they grow very slowly and do not spread to other parts of the body. Information about craniopharyngioma, another type pituitary tumor, can be found in another summary (refer to the PDQ summaries on Adult Brain Tumors Treatment and Childhood Brain Tumors Treatment for more information on craniopharyngioma).

If a pituitary tumor is found, the pituitary gland may be making too many hormones. This can cause other problems in the body. Tumors that make hormones are called functioning tumors, while those that do not make hormones are called nonfunctioning tumors.

Certain pituitary tumors can cause a disease called Cushing's disease, in which too many hormones called glucocorticoids are released into the bloodstream. This causes fat to build up in the face, back, and chest, and the arms and legs to become very thin. Other symptoms include too much sugar in the blood, weak muscles and bones, a flushed face, and high blood pressure. Other pituitary tumors can cause a condition called acromegaly. Acromegaly means that the hands, feet, and face are larger than normal; in very young people, the whole body may grow much larger than normal. Another type of pituitary tumor can cause the breasts to make milk, even though a woman may not be pregnant; periods may stop as well.

Thyroid cancers: Cancer of the thyroid gland accounts for approximately 1.1% of all malignancies. Its incidence in women is more than twice that in men, and it can occur at any age. Radiation to the head and neck region for benign conditions (such as acne and tonsillitis) during childhood or adolescences is the only well-documented factor in the etiology of thyroid cancer. There is generally a prolonged latency period between radiation exposure and the development of thyroid cancer (over 20 years) with risk increasing as the latency period increases. Patients with an endemic goiter are also thought to be at increased risk for this malignancy.

Other major Cancers are:
Gastrointestinal Cancers
Gynecological Cancers
Head & Neck Cancers
Leukemia
Lung Cancers
Lymphomas
Metastases
Myelomas
Pediatric Cancers
Penile Cancer
Prostate Cancer
Sarcomas
Skin Cancer
Testicular Cancer
Thyroid Cancer
Urinary Tract Cancers

THE PRODUCT:

COMBICARE is a innovative herbal preparation that addresses the spread of cancerous cells or matastasis. It has two modes of action:
Immunomodulatory activity
Anti-metastatic activity.

COMBICARE is prepared from selected herbs based on years of research. These herbs have immunomodulatory properties and check the spread of cancerous cells by binding to the E-cadherin protein’s external surface thereby blocking the adhesion of the cancerous cell to good tissue. This process inhibits the spread of cancer and the activity of the herbs in modulating the immune system ensures that the body natural defenses allow the various bio chemical changes in the body to return to normal. The antioxidant capacity of herbs has been recognized by the international medical community as playing a significant role in the protection against cancer as well as in checking the spread of cancer by acting as “free radical scavengers”.

COMBICARE is a unique product as it addresses both issues of protecting normal cells from being targeted by cancer cells, and well as destroying free radicals that cause cancer.

COMPOSITION:

Each Capsule of COMBICARE contains:

Withania somnifera extract
Tinospora cordifolia extract
Ocimum sanctum extract
Citrus aurantium extract
Azadirachta indica extract
Curcuma longa extract
Boerhavia diffusa extract
Piper Longum extract

RESULTS:

Tumor growth, angiogenesis, and spontaneous metastasis in vivo were statistically significantly reduced in mice fed MCP. In vitro, MCP inhibited HUVEC morphogenesis (capillary tube formation) in a dose-dependent manner. In vitro, MCP inhibited the binding of galectin-3 to HUVECs: At concentrations of 0.1% and 0.25%, MCP inhibited the binding of galectin-3 (10 micro g/mL) to HUVECs by 72.1% (P =.038) and 95.8% (P =.025), respectively, and at a concentration of 0.25% it inhibited the binding of galectin-3 (1 micro g/mL) to HUVECs by 100% (P =.032). MCP blocked chemotaxis of HUVECs toward galectin-3 in a dose-dependent manner, reducing it by 68% at 0.005% (P<.001) and inhibiting it completely at 0.1% (P<.001). Finally, MCP also inhibited adhesion of MDA-MB-435 cells, which express galectin-3, to HUVECs in a dose-dependent manner. CONCLUSIONS: MCP, given orally, inhibits carbohydrate-mediated tumor growth, angiogenesis, and metastasis in vivo, presumably via its effects on galectin-3 function. These data stress the importance of dietary carbohydrate compounds as agents for the prevention and/or treatment of cancer.

Researchers at Texas A&M University-Kingsville Citrus Center, Weslaco, TX 78596, USA.undertook a study to characterize the pectin from four citrus species and to determine their in vitro inhibitory activities on the binding of fibroblast growth factor (FGF) to the FGF receptor (FGFR). Pectin from various parts of lemon, grapefruit, tangerine, and orange were isolated and characterized. Tangerine had the highest pectin content among the four citrus species. Segment membrane contained as much as or more pectin than flavedo/albedo. Anhydrogalacturonic content was highest in pectin from segment membrane of tangerine and flavedo/albedo of grapefruit. Lemon pectin contained the highest methoxyl content (MC), and grapefruit contained the largest proportion of lower molecular weight (<10000 Da) pectin. Tangerine contained the highest neutral sugar in both flavedo/albedo and segment membrane. The interdependency of heparin on factor-receptor interaction provides a means for identifying new antagonists of growth factor activity and thus for treatment of various diseases. These results showed that pectin significantly inhibited the binding of FGF-1 to FGFR1 in the presence of 0.1 microg/mL heparin. The pectin from the segment membrane of lemon was the most potent inhibitor. The inhibition activity was significantly correlated with sugar content, MC, and size of pectin. Kinetic studies revealed a competitive nature of pectin inhibition with the heparin, a crucial component of the FGF signal transduction process. The observation that the heparin-dependent biological activity of FGF signal transduction is antagonized by citrus pectin should be further investigated for the use of these pectins as anti-growth factor agents for potential health benefits.

ACTION OF THE FORMULATION:

Protecting against Free Radical damage.
Restores cellular integrity.
Regulating the immune response.
Reducing metastasis

DOSAGE:

1-2 Capsules, two to three times a day

CONTRADICTIONS:

None reported

PREGNANCY:

Safe to take under medical supervision.

REFRENCES

Arhuma|Breathex|Coeurcare|Combicare|Dicid|Dialo|Hypercool

Femipose|Figofit|Fluwin|Livup|Memogen|Touxnil|Vitex